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The SOCA officials wished to remain anonymous.
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What Happened: The study was a randomized, double-blind, placebo-controlled trial using Spartalizumab — an investigational monoclonal antibody, alongside Tafinlar and Mekinist. The evaluation was conducted in three parts and the declared results were from the final stages of testing, Novartis said. Why It Matters: The company noted it intended to continue Spartalizumab development, despite negative clinical trial results.
Price Action: Novartis shares closed 0. The stock gained 0. Novartis AG announced on Saturday that its investigational spartalizumab immunotherapy drug combined with Tafinlar and Mekinist therapies failed to meet its primary endpoint in a late-stage trial for the treatment of a type of advanced skin cancer. The trial was conducted among untreated patients with unresectable or metastatic stage IV BRAF V mutation-positive cutaneous melanoma, compared to the treatment of Tafinlar and Mekinist alone.
Spartalizumab is an investigational monoclonal antibody directed against the human programmed death-1 PD-1 receptor. In addition, the Swiss drugmaker said that it will continue to explore new uses for immunotherapy in cancer treatment, including the ongoing development of spartalizumab, across a range of tumor types. Novartis shares have now recouped a large chunk of their losses from earlier this year but they are still down 8. Adlai Nortye Ltd. Narasimhan, a U.